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If you are sensitive to allergen such as ragweed pollen or chemical such as paint, once contacted it will precipitate your immune system into releasing histamines from the mast cells and attaches to the receptors in the surrounding blood vessels causing them to enlarge. Histamine will also bind to other receptors, which causes redness, swelling 
Hives – Causes & Remedies Urticaria , the medical name for hives, is an outbreak of small, burning or itching swelling or flushing (redness) on the skin. They can be horribly itchy and are usually followed with a stinging or burning sensation. Hives usually appear unexpectedly for unknown reasons or due to the body’s reaction |
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